Jennifer Garner plays Christy Beam from Burleson, Texas, wife to hunky veterinarian Kevin and mother to three adorable daughters, Abbie, Adelynn and Annabel (aka Anna). It's ten-year-old Anna that's the girl who becomes interminably ill, unable to keep down food and showing signs of gastrointestinal bloating that is only growing larger by the day. Doctors are perplexed by the condition and misdiagnose it as something that will pass and be unconcerned about, but Christy knows it's something more and continues to get several opinions until finally coming across someone that can help in the form of pediatric gastroenterologist Dr. Samuel Nurko. The problem is that Dr. Nurko is so overbooked that there is a nine-month waiting list to see him, with his schedule only opening up when one of his patients dies. Knowing that Anna's chances to even make it nine months seems slim, Christy heads out to the children's hospital in Boston on the hope to get the only man with the possibility of helping out with a possibly incurable disease (called pseudo-obstruction motility disorder) to take Anna on as a patient.